MouseCre
Mouse Cre and CreERT2 zoo

Repository

The CreERT2 Zoo is a repository for the collection and distribution of relevant mutant mouse strains essential for basic biomedical research. This mouse resource from the Institut Clinique de la Souris (PHENOMIN-ICS) consists in a collection of about fifty cell specific Tamoxifen inducible Cre driver lines. All lines are available to the scientific community with a materiel transfert agreement (MTA) and available as alive animals and/or frozen materials (embryos/sperm).

To request a line please contact us by email at

Additionally, about fifty CreERT2 knock-in lines are available. As a partner of EUCOMMtools, PHENOMIN-ICS generated them with C57BL/6N Cre knock-in ES cell lines. Their Cre expression patterns are currently under documentation and annotation (named "to be defined" in the summary table) at post-natal day 14 and post-natal day 56. Annotation data will be available soon.


Target cell and tissue Gene Promoter Reference Mutations and alleles Availability Funding program
adipose tissue Adiponectin, C1Q and collagen domain containing hADIPOQ NCBI:9370 transgenic (BAC) Embryo cryopreserved
adipose tissue Fatty acid binding protein 4 adipocyte hFABP4 NCBI:2167 transgenic (BAC) Embryo cryopreserved
adipose tissue Fabp4 mFabp4 MGI:88038 Other Embryo cryopreserved
adipose tissue Uncoupling protein 1 (mitochondrial, proton carrier) hUCP1 NCBI:7350 transgenic (BAC) Embryo cryopreserved
adipose tissue Delta-like 1 homolog mDlk1 MGI:94900 NCBI:13386 transgenic (BAC) Embryo cryopreserved
alpha cells Glucagon mGcg MGI:95674 NCBI:14526 transgenic (plasmid) Embryo cryopreserved
beta cells Insulin 1 mIns1 MGI:96572 NCBI:16333 transgenic (plasmid) Embryo cryopreserved
cardiovascular system Myosin heavy polypeptide 6 cardiac muscle alpha mMyh6 MGI:97255 NCBI:17888 transgenic (BAC) Embryo cryopreserved
central nervous system Neurofilament light polypeptide mNefl MGI:97313 NCBI:18039 transgenic (BAC) Embryo cryopreserved
central nervous system Calcium/calmodulin dependent protein kinase II alpha mCamkIIa MGI:88256 NCBI:12322 transgenic (plasmid) Embryo cryopreserved
central nervous system Purkinje cell protein 2 (L7) mPcp2 MGI:97508 NCBI:18545 transgenic (BAC) Embryo cryopreserved
central nervous system Nestin mNes MGI:101784 NCBI:18008 transgenic (BAC) Embryo cryopreserved
central nervous system Calcium/calmodulin dependant protein Kinase II alpha hCAMKIIa NCBI:815 transgenic (BAC) Embryo cryopreserved
central nervous system Enolase 2, gamma neuronal mEno2 MGI:95394 NCBI:13807 transgenic (BAC) Embryo cryopreserved
central nervous system Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 mSlc6a3 MGI:94862 NCBI:13162 transgenic (BAC) Embryo cryopreserved
central nervous system SRY-box containing gene 2 mSox2 MGI:98364 NCBI:20674 transgenic (BAC) Embryo cryopreserved
central nervous system Plasmacytoma expressed transcript 1 mPet1 MGI:102766 NCBI:107689 transgenic (BAC) Embryo cryopreserved
exocrine pancreatic cells Elastase 1 pancreatic mCela1 MGI:95314 NCBI:109901 transgenic (BAC) Embryo cryopreserved
immune system CD4 antigen mCd4 MGI:88335 NCBI:12504 transgenic (BAC) Embryo cryopreserved
immune system Lymphocyte protein tyrosine kinase mLck MGI:96756 NCBI:16818 transgenic (BAC) Embryo cryopreserved
immune system Macrosialin mCd68 MGI:88342 NCBI:12514 transgenic (BAC) Embryo cryopreserved
immune system Glycoprotein 1b alpha polypeptide mGp1ba MGI:1333744 NCBI:14723 transgenic (BAC) Embryo cryopreserved
immune system CD19 molecule hCD19 NCBI:930 transgenic (BAC) Embryo cryopreserved
immune system Platelet factor 4 mPf4 MGI:1888711 NCBI:56744 transgenic (BAC) Embryo cryopreserved
integumental system Keratin 14 mKrt14 MGI:96688 NCBI:16664 transgenic (BAC) Embryo cryopreserved
integumental system Keratin 5 hKRT5 NCBI:3852 transgenic (BAC) Embryo cryopreserved
integumental system Keratin 10 mKrt10 MGI:96685 NCBI:16661 transgenic (BAC) Embryo cryopreserved
kidney Kidney androgen regulated protein mKap MGI:96653 NCBI:16483 transgenic (BAC) Embryo cryopreserved
macrophages Lysozyme mLyzs MGI:96897 NCBI:17105 transgenic (BAC) Embryo cryopreserved
mucosa (glandular stomach) Ghrelin mGhrl MGI:1930008 NCBI:58991 transgenic (BAC) Embryo cryopreserved
myocytes Troponin I, skeletal, fast 2 mTnni2 MGI:105070 NCBI:21953 transgenic (BAC) Embryo cryopreserved
oocyte Zona pellucida glycoprotein mZp3 MGI:99215 NCBI:22788 transgenic (BAC) Embryo cryopreserved
skeletal system Procollagen type I alpha1 mCol1a1 MGI:88467 NCBI:12842 transgenic (BAC) Embryo cryopreserved
skeletal system Acid phosphatase 5 tartrate resistant mAcp5 MGI:87883 NCBI:11433 transgenic (BAC) Embryo cryopreserved
skeletal system Bone gamma carboxyglutamate protein 1 mBglap1 MGI:88156 NCBI:12096 transgenic (BAC) Embryo cryopreserved
spermatocytes Phosphoglycerate kinase 2 mPgk2 MGI:97563 NCBI:18663 transgenic (BAC) Embryo cryopreserved
ubiquitous Protein phosphatase 1A, magnesium dependent, alpha isoform mPpm1a MGI:99878 NCBI:19042 transgenic (BAC) Embryo cryopreserved
ubiquitous ERT2-iCre-ERT2 DiCre MGI:3793441 Other
immune system CD19 molecule hCD19 NCBI:930 transgenic (BAC) Embryo cryopreserved
adipose tissue Adiponectin, C1Q and collagen domain containing hADIPOQ NCBI:9370 transgenic (BAC) Embryo cryopreserved
ubiquitous Protein phosphatase 1A, magnesium dependent, alpha isoform mPpm1a MGI:99878 NCBI:19042 transgenic (BAC) Embryo cryopreserved
adipose tissue Delta-like 1 homolog mDlk1 MGI:94900 NCBI:13386 transgenic (BAC) Embryo cryopreserved
central nervous system Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 mSlc6a3 MGI:94862 NCBI:13162 transgenic (BAC) Embryo cryopreserved
central nervous system Plasmacytoma expressed transcript 1 mPet1 MGI:102766 NCBI:107689 transgenic (BAC) Embryo cryopreserved
central nervous system SRY-box containing gene 2 mSox2 MGI:98364 NCBI:20674 transgenic (BAC) Embryo cryopreserved
skeletal system Procollagen type I alpha1 mCol1a1 MGI:88467 NCBI:12842 transgenic (BAC) Embryo cryopreserved
kidney Kidney androgen regulated protein mKap MGI:96653 NCBI:16483 transgenic (BAC) Embryo cryopreserved
central nervous system Purkinje cell protein 2 (L7) mPcp2 MGI:97508 NCBI:18545 transgenic (BAC) Embryo cryopreserved
myocytes Troponin I, skeletal, fast 2 mTnni2 MGI:105070 NCBI:21953 transgenic (BAC) Embryo cryopreserved
beta cells Insulin 1 mIns1 MGI:96572 NCBI:16333 transgenic (plasmid) Embryo cryopreserved
integumental system Keratin 5 hKRT5 NCBI:3852 transgenic (BAC) Embryo cryopreserved
adipose tissue Uncoupling protein 1 (mitochondrial, proton carrier) hUCP1 NCBI:7350 transgenic (BAC) Embryo cryopreserved
immune system CD4 antigen mCd4 MGI:88335 NCBI:12504 transgenic (BAC) Embryo cryopreserved
central nervous system Calcium/calmodulin dependent protein kinase II alpha mCamkIIa MGI:88256 NCBI:12322 transgenic (plasmid) Embryo cryopreserved
central nervous system Calcium/calmodulin dependant protein Kinase II alpha hCAMKIIa NCBI:815 transgenic (BAC) Embryo cryopreserved
central nervous system Nestin mNes MGI:101784 NCBI:18008 transgenic (BAC) Embryo cryopreserved
adipose tissue Fatty acid binding protein 4 adipocyte hFABP4 NCBI:2167 transgenic (BAC) Embryo cryopreserved
exocrine pancreatic cells Elastase 1 pancreatic mCela1 MGI:95314 NCBI:109901 transgenic (BAC) Embryo cryopreserved
skeletal system Acid phosphatase 5 tartrate resistant mAcp5 MGI:87883 NCBI:11433 transgenic (BAC) Embryo cryopreserved
immune system Platelet factor 4 mPf4 MGI:1888711 NCBI:56744 transgenic (BAC) Embryo cryopreserved
integumental system Keratin 10 mKrt10 MGI:96685 NCBI:16661 transgenic (BAC) Embryo cryopreserved
cardiovascular system Myosin heavy polypeptide 6 cardiac muscle alpha mMyh6 MGI:97255 NCBI:17888 transgenic (BAC) Embryo cryopreserved
immune system Lymphocyte protein tyrosine kinase mLck MGI:96756 NCBI:16818 transgenic (BAC) Embryo cryopreserved
integumental system Keratin 14 mKrt14 MGI:96688 NCBI:16664 transgenic (BAC) Embryo cryopreserved
central nervous system Enolase 2, gamma neuronal mEno2 MGI:95394 NCBI:13807 transgenic (BAC) Embryo cryopreserved
immune system Glycoprotein 1b alpha polypeptide mGp1ba MGI:1333744 NCBI:14723 transgenic (BAC) Embryo cryopreserved
immune system Macrosialin mCd68 MGI:88342 NCBI:12514 transgenic (BAC) Embryo cryopreserved
skeletal system Bone gamma carboxyglutamate protein 1 mBglap1 MGI:88156 NCBI:12096 transgenic (BAC) Embryo cryopreserved
macrophages Lysozyme mLyzs MGI:96897 NCBI:17105 transgenic (BAC) Embryo cryopreserved
spermatocytes Phosphoglycerate kinase 2 mPgk2 MGI:97563 NCBI:18663 transgenic (BAC) Embryo cryopreserved
oocyte Zona pellucida glycoprotein mZp3 MGI:99215 NCBI:22788 transgenic (BAC) Embryo cryopreserved
mucosa (glandular stomach) Ghrelin mGhrl MGI:1930008 NCBI:58991 transgenic (BAC) Embryo cryopreserved
alpha cells Glucagon mGcg MGI:95674 NCBI:14526 transgenic (plasmid) Embryo cryopreserved
central nervous system Neurofilament light polypeptide mNefl MGI:97313 NCBI:18039 transgenic (BAC) Embryo cryopreserved
adipose tissue Fabp4 mFabp4 MGI:88038 Other Embryo cryopreserved
ubiquitous ERT2-iCre-ERT2 DiCre MGI:3793441 Other

informations on the colorimetric floxed reporter mice are indicated in Soriano P, Nat Genet. 1999 Jan;21(1):70-1 Generalized lacZ expression with the ROSA26 Cre reporter strain