Mouse Cre and CreERT2 zoo


The CreERT2 Zoo is a repository for the collection and distribution of relevant mutant mouse strains essential for basic biomedical research. This mouse resource from the Institut Clinique de la Souris (PHENOMIN-ICS) consists in a collection of about fifty cell specific Tamoxifen inducible Cre driver lines. All lines are available to the scientific community with a materiel transfert agreement (MTA) and available as alive animals and/or frozen materials (embryos/sperm).

To request a line please contact us by email at

Additionally, about fifty CreERT2 knock-in lines are available. As a partner of EUCOMMtools, PHENOMIN-ICS generated them with C57BL/6N Cre knock-in ES cell lines. Their Cre expression patterns are currently under documentation and annotation (named "to be defined" in the summary table) at post-natal day 14 and post-natal day 56. Annotation data will be available soon.

Target cell and tissue Gene Promoter Reference Mutations and alleles Availability Funding program
adipose tissue Adiponectin, C1Q and collagen domain containing hADIPOQ NCBI:9370 transgenic (BAC) Cryopreserved
adipose tissue Fatty acid binding protein 4 adipocyte hFABP4 NCBI:2167 transgenic (BAC) Cryopreserved
adipose tissue Fabp4 mFabp4 MGI:88038 Other Cryopreserved
adipose tissue Uncoupling protein 1 (mitochondrial, proton carrier) hUCP1 NCBI:7350 transgenic (BAC) Cryopreserved
adipose tissue Delta-like 1 homolog mDlk1 MGI:94900 NCBI:13386 transgenic (BAC) Cryopreserved

informations on the colorimetric floxed reporter mice are indicated in Soriano P, Nat Genet. 1999 Jan;21(1):70-1 Generalized lacZ expression with the ROSA26 Cre reporter strain