MouseCre
Mouse Cre and CreERT2 zoo

Repository

The CreERT2 Zoo is a repository for the collection and distribution of relevant mutant mouse strains essential for basic biomedical research. This mouse resource from the Institut Clinique de la Souris (PHENOMIN-ICS) consists in a collection of about fifty cell specific Tamoxifen inducible Cre driver lines. All lines are available to the scientific community with a materiel transfert agreement (MTA) and available as alive animals and/or frozen materials (embryos/sperm).

To request a line please contact us by email at

Additionally, about fifty CreERT2 knock-in lines are available. As a partner of EUCOMMtools, PHENOMIN-ICS generated them with C57BL/6N Cre knock-in ES cell lines. Their Cre expression patterns are currently under documentation and annotation (named "to be defined" in the summary table) at post-natal day 14 and post-natal day 56. Annotation data will be available soon.


Target cell and tissue Gene Promoter Reference Mutations and alleles Availability Funding program
central nervous system Neurofilament light polypeptide mNefl MGI:97313 NCBI:18039 transgenic (BAC) Cryopreserved
central nervous system Calcium/calmodulin dependent protein kinase II alpha mCamkIIa MGI:88256 NCBI:12322 transgenic (plasmid) Cryopreserved
central nervous system Purkinje cell protein 2 (L7) mPcp2 MGI:97508 NCBI:18545 transgenic (BAC) Cryopreserved
central nervous system Nestin mNes MGI:101784 NCBI:18008 transgenic (BAC) Cryopreserved
central nervous system Calcium/calmodulin dependant protein Kinase II alpha hCAMKIIa NCBI:815 transgenic (BAC) Cryopreserved
central nervous system Enolase 2, gamma neuronal mEno2 MGI:95394 NCBI:13807 transgenic (BAC) Cryopreserved
central nervous system Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 mSlc6a3 MGI:94862 NCBI:13162 transgenic (BAC) Cryopreserved
central nervous system SRY-box containing gene 2 mSox2 MGI:98364 NCBI:20674 transgenic (BAC) Cryopreserved
central nervous system Plasmacytoma expressed transcript 1 mPet1 MGI:102766 NCBI:107689 transgenic (BAC) Cryopreserved

informations on the colorimetric floxed reporter mice are indicated in Soriano P, Nat Genet. 1999 Jan;21(1):70-1 Generalized lacZ expression with the ROSA26 Cre reporter strain